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Post-surgical pain control is often inadequate and opioid-dependent. Opioid-based pain-relief drugs increase the risk of opioid abuse by 14×1. Surgeons, patients, and public health authorities want a non-opioid drug that can: Lower post-operative pain Speed rehabilitation times Reduce post-operative visits Lower opioid use, side-effects, and risk of addiction Surgeons, patients, and public health authorities want … Read more

Studies on the Science of Buffering The following are just some of the published research articles on buffering, or pH-balancing, of local anesthetic. Taking the ‘ouch’ out – effect of buffering commercial xylocaine on infiltration and procedure pain – a prospective, randomised, double-blind, controlled trial Younis I, Bhutiani RP View research Sodium Bicarbonate Attenuates Pain … Read more

Studies consistently show that pH-balanced local anesthetics provide improved comfort and much faster onset of anesthesia New Research British Journal of Oral and Maxillofacial Surgery Publishes Study Showing Statistically Significant Benefits of Buffering Local Anesthetics A large body of research shows that removing the acid from local anesthetics produces faster onset, less injection pain, and … Read more

Current dental injections are too painful, too slow, and too unreliable. Each Year, Patients Suffer Nearly 2 Billion Dental Injections Dental anesthetic injections are notoriously slow-acting, painful, and unreliable. They are stressful for both patients and dentists, and for good reason: The acid preservative in local anesthetic drugs causes pain during injection and a delayed … Read more